Content warning: This conversation is about self-harm and suicide and may be distressing for some listeners. If you or someone you know is affected by these issues, please visit https://findahelpline.com/ a global database of support lines associated with the International Association for Suicide Prevention.

How effective are psychosocial interventions for self-harm and do they work differently for men and women? In this episode we discuss new evidence on sex differences in outcomes and the challenges of engaging men in mental health support. We also hear a lived experience perspective, offering insight into how support can be made more accessible and meaningful.

Click here to read the full article: https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(26)00018-9/fulltext

In this episode, Deputy Editor Ivana Nedic is joined by Dr Emiliano Calvo to discuss the rapidly evolving landscape of systemic cancer therapies. Ahead of the upcoming Series in The Lancet Regional Health – Europe, they explore its four key pillars: next-generation antibody-based therapies, antibody-drug conjugates, oncolytic viruses and cancer vaccines, and emerging cell therapies for solid tumours. The conversation examines the scientific advances driving these approaches, the challenges of toxicity management and equitable access across Europe, and how these innovative modalities may be sequenced and combined in the years ahead to reshape cancer care.

Join Senior Editor Stephanie Becker in an insightful conversation with Santiago Madero as they explore the evolving perspectives on psychedelic treatments, the latest developments in regulatory frameworks, and advances in psychedelic research.

This episode delves into the complex debates surrounding the therapeutic potential and experiential aspects of psychedelic treatments, highlighting the challenges and opportunities for their safe and effective implementation and regulation.

Click here to read the full article: https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00329-1/fulltext

In this anniversary episode, Editor-in-Chief Pooja Jha is joined by Deputy Editor Ivana Nedic and Senior Editor Stephanie Becker to mark five years of The Lancet Regional Health – Europe. Together, they reflect on key milestones from the journal’s first five years, look ahead to priorities for 2026, including new Series and collaborations, and discuss highlights from the January issue. Tune in for a conversation on how the journal has evolved, what lies ahead for regional health research in Europe, and the editorial thinking shaping the year to come.

The lancet Regional Health – Europe

What are the risks of a future surge in variant Creutzfeldt-Jakob disease cases?

Join Senior Editor Stephanie Becker as she sits down with Professor Simon Mead to discuss the history of the bovine spongiform encephalopathy epidemic, what updated estimates for future vCJD cases mean for public health policy, and advances in biomarkers and treatments.

Click here to read the full article: https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00294-7/fulltext

Alan Fraser and Stefan James talk to Acting Deputy Editor Heather Brown about the evidence needed for regulatory approval of high-risk medical devices, such as stents, valves, pacemakers, and orthopaedic implants. The CORE-MD project makes recommendations for what evidence should be needed and calls for greater transparency and predictability.

Click here to read the full article: https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00252-2/fulltext

In this episode, Senior Editor Ivana Nedic is joined by Professor Sir Graham Thornicroft to discuss the urgent need to transform mental health in Europe.

Building on the newly launched Transforming Mental Health in Europe Series in The Lancet Regional Health – Europe, they explore its four key themes: persistent gaps in care, the mental health of healthcare workers, challenges facing children and young people, and the case of Central and Eastern Europe.

The conversation highlights priority areas for action, drawing on European examples, and considers how policy and services can drive meaningful and lasting change in mental health systems.

Read the Series:

https://www.thelancet.com/series-do/mental-health-europe?dgcid=buzzsprout_icw_podcast_lanepemheurope25_lanepe

Raffaele Bugiardini and Karen Padilla Cabrera talk to Acting Deputy Editor Heather Brown about a new Series of papers on the inequalities and disparities that continue to undermine equity in cardiovascular health, particularly for women, racial and ethnic minorities, older adults, and individuals with mental health conditions.

Read the Series here:

https://www.thelancet.com/series-do/inequalities-disparities-cvd?dgcid=buzzsprout_icw_podcast_lanepecardiohealth25_lanepe