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In this issue, you’ll learn what the latest technological flops, fizzles, and flame outs tell us about innovation. You’ll hear how the past year ushered in progress in developing hardware and software capable of human feats of intelligence. You’ll learn how a wireless transmitter could give paralyzed people a practical way to control TVs, computers, or wheelchairs with their thoughts. You’ll hear how software that turns data into written text could help us make sense of a coming tsunami of data. You’ll learn what’s next for the inventor of Gorilla Glass. You’ll hear about how a wireless technology more than 10 times faster than the best Wi-Fi is coming to market this year.

In this issue, you’ll hear how the way the Land of the Rising Sun built and lost its dominance in photovoltaics shows just how vulnerable renewables remain to changing politics and national policies. You’ll learn how researchers are taking a new approach at unlocking Autism’s secrets. You’ll hear about a group of journalists and researchers that are venturing into the ugly corners of the Internet in an effort to expose racists, creeps, and hypocrites. And you’ll learn how severe droughts are forcing researchers to rethink how technology can increase the supply of fresh water.

In this issue, you’ll learn why the disparity between the rich and everyone else is larger than ever in the United States and increasing in much of Europe. You’ll hear whether an aging corporation’s adventures in fundamental physics can open an era of unimaginably powerful computers. You’ll learn how China will dominate the future of genetically modified food—despite the resistance of its population. And you’ll hear how letting go of an obsession with net neutrality could free technologists to make online services even better.

In this Special Issue, Technology Review’s 35 Innovators Under 35. All 35 of these people are doing exciting work that could shape their fields for decades. But they’re solving problems in remarkably different ways. We consider some of them to be primarily Inventors; they’re immersed in building new technologies. Others we call Visionaries, because they’re showing how technologies could be put to new or better uses. Humanitarians are using technology to expand opportunities or inform public policy. Pioneers are doing fundamental work that will spawn future innovations; such breakthroughs will be taken up by tomorrow’s Entrepreneurs, people who are building new tech businesses. Everyone on the list was nominated either by the public or by MIT Technology Review’s editors. Some got our attention when they were picked by our international publishing partners as Innovators Under 35 for their regions. After our editors pared the roughly 500 nominees to 80 finalists, outside judges rated the originality and impact, or potential impact, of their work; those scores guided the editors as they crafted the list.

In this issue, you’ll learn about Technology Review’s 10 breakthrough Technologies of 2014.

In this issue, you’ll learn why we will need genetically modified foods. You’ll learn about an online file storage system designed to reshape industries. You’ll hear how microchips modeled on the brain may excel at tasks that baffle today’s computers. You’ll learn how pregnant women now have an easy and risk-free way to identify genetic flaws in their fetuses. And you’ll hear about Facebook’s commitment to connectivity.

In this issue, you’ll learn why we need a civic solution to privacy. You’ll hear what car makers are really working on – it’s not self-driving cars. You’ll learn why the community that built the largest encyclopedia in history is shrinking. And you’ll hear why today’s medicines can cost hundreds of thousands of dollars a year.

In this issue, you’ll learn how the lead architect of Sony Computer Entertainment will define the next blockbuster game console. You’ll hear how Samsung’s new smart watch may be the most polished effort yet. You’ll learn how startups are using sound waves to let mobile gadgets transfer data quickly and efficiently. You’ll learn why it could take years for 3-D gesture-control to catch on with consumers and app developers. You’ll hear how Silicon chips with optical technology are allowing a new form of superfast data connection. And you’ll hear news from the worlds of Biomedicine, Technology and Communications.

For our 13th annual celebration of people who are driving the next generation of technological breakthroughs, we’re presenting the stories in a new way. We’ve grouped them by categories that reflect the variety of approaches that people can take to big problems. First we introduce you to Inventors, who are creating new technologies. Next come Entrepreneurs, who are turning technologies into viable businesses. Then meet the Visionaries, who are anticipating how technologies can make life better, while Humanitarians are concentrating on expanding opportunities. Finally, the Pioneers are exploring new frontiers, setting the stage for future innovations.

In this issue, you’ll learn why Silicon Valley has never been successfully reproduced. You’ll hear the secret to becoming the next tech hot spot. You’ll learn how Beijing is being turned into a technology powerhouse….

Technology Review is the United State's oldest technology magazine. And in the last few years, TR has undergone a dramatic transformation, shifting its focus to innovation - the process by which humanity continuously upgrades its tools and techniques. Each issue concentrates on four major fields of innovation: biotechnology, information technology, material science, and nanotechnology.

In this issue, you’ll hear what happened when one man pinged the whole internet. You’ll hear why Google is breaking its own restrictions. You’ll learn how researchers have come up with a way to mine cell-phone data while avoiding privacy pitfalls. You’ll hear why companies that make industrial control systems have finally begun to pay more attention to security issues. You’ll learn about Florida’s first full-scale smart grid technology system. And you’ll hear news from the worlds of Biomedicine, Technology and Communications.

In this issue, you’ll learn how Artificial intelligence is finally getting smart. You’ll hear about the next frontier of the genome revolution. You’ll learn about a maverick neuroscientist who believes he has deciphered the code by which the brain forms long-term memories. You’ll hear about the debate over what our responsibilities and duties are to help safeguard the distant future from global warming. And you’ll learn why we need technology that enhances human drivers’ abilities rather than making those abilities increasingly obsolete.

In this issue, you’ll learn how developing nations are putting nuclear on fast-forward. You’ll hear about a new kind of molten-salt reactor that is designed to overcome the major barriers to nuclear power. You’ll learn why securing critical infrastructure needs to go far beyond the measures in President Obama’s executive order. You’ll hear how the sequencing of a complete human genome may soon cost less than an iPhone. You’ll learn about Facebook’s database that describes as many things as possible.

You’ll hear how pro-manufacturing advisors have the ear of the president. You’ll hear how robots could be replacing low-wage workers. You’ll learn how breakthroughs in hardware and software brought us usability advances, faster chips, and gesture control. You’ll hear two articles on China’s technological outlook for the year. You’ll learn about a new processor that could help usher in the next wave of mobile communication breakthroughs. And you’ll hear news from the worlds of Biomedicine, Technology and Communications.

In this issue, you’ll learn how one man may have just started a race to discover alien life on the Red Planet. You’ll hear about a jamming technique that could take out an entire city’s mobile service. You’ll learn why Microsoft may be invading China’s smart-phone market. You’ll hear about Microsoft’s mobile era dilemma. You’ll hear three different articles about online education. And you’ll hear news from the worlds of Biomedicine, Technology and Communications.

In this issue, learn why we are having difficulties solving the big problems. You’ll learn about United States’ plan of sending astronauts to Mars in 2030. You’ll hear about the looming Alzheimer's health-care disaster. You’ll learn whether online colleges are just a fad or the change that higher education needs. And you’ll learn how solar-powered microgrids could help bring power to millions of the World’s poorest.

In this issue, you’ll hear how venture capital has failed to be the financial engine of American innovation. You’ll learn why a research agency’s shift in focus to alternative energy has put them in the political crosshairs. You’ll hear how a blood test could herald in a new wave of noninvasive prenatal screenings. You’ll learn how market leaders can quickly turn into market has-beens.

Welcome to Technology Review’s Special Edition for September 2012 on the 35 Innovators Under the Age of 35. Some members of our latest list of young innovators from around the world have developed consumer Web services you might have used, such as Spotify or Dropbox. Others are making more fundamental breakthroughs that have yet to be commercialized, such as more efficient engines or improvements in optical communications. And a few are blazing trails in fields that didn’t exist before, like pop-up fabrication of tiny machines, or cameras that can see around corners. But all 35 of them have something significant in common: their work is likely to be influential for a very long time. We hope that these stories about them surprise and inspire you.

In this issue, you’ll hear about the future of the computer industry. You’ll learn why Google’s Nexus 7 is going to make plenty of friends. You’ll hear why the advertising industry is battling some of technology’s biggest companies. You’ll learn whether Europe's strict stance on protecting people's data is costing businesses or creating new opportunities. You’ll hear how candidates are matching voter records with sophisticated online tracking to target their ads. And you’ll hear news from the worlds of Biomedicine, Technology and Communications.